Coffee’s Effects on Sex Hormones in Men and Women

Source: University of Oulu / European Journal of Nutrition
Author: Qahwa World
Date: August 31, 2026

Finnish Study: Coffee’s Effects on Sex Hormones in Men and Women

  • Finnish study links regular coffee consumption to healthier body composition in both sexes.
  • Significant increase in total testosterone and SHBG in men.
  • Increased SHBG and decreased free androgens in women.
  • Lower levels of branched-chain amino acids (BCAAs) in both sexes.
  • Lower BCAAs indicate reduced risk of insulin resistance, diabetes, and heart disease.
  • The study included over 2,200 participants aged 46.

A new scientific study by researchers at the University of Oulu in Finland has found that regular coffee consumption is linked to healthier body composition. Coffee drinkers had lower stored fat and greater muscle mass compared to non-drinkers. The study also revealed surprising hormonal effects that differ between men and women.

The study was published in the European Journal of Nutrition. It analyzed data from over 2,200 participants aged 46. The research team examined the relationship between coffee consumption, heart health indicators, metabolic outcomes, and sex hormone levels.

A Hormonal Signature Linked to Coffee

The results revealed a “hormonal signature” linked to coffee. The strongest effects were seen in men. Coffee consumption was associated with improved glucose and insulin regulation. Men also showed higher levels of total testosterone and sex hormone-binding globulin (SHBG).

In women, coffee was linked to increased SHBG and decreased free androgens. These hormones are responsible for libido, mood, and the health of the body, hair, and bones.

Hormonal Effects of Coffee by Gender
Gender Hormonal Effect
Men Increased total testosterone, increased SHBG, improved glucose and insulin regulation
Women Increased SHBG, decreased free androgens

Hormonal Changes Independent of Lifestyle

Lead researcher Luca Viruisti, a nutrition specialist, explained that these hormonal changes remained significant even after excluding lifestyle factors and body mass index. This suggests coffee has a direct effect on the hormonal system, not just a result of other healthy habits.

Lower Branched-Chain Amino Acids (BCAAs)

The results showed lower levels of branched-chain amino acids (BCAAs) in the blood of coffee drinkers of both sexes. Researchers noted that lower levels of these amino acids are a positive indicator. Chronic elevation of BCAAs is linked to risks of insulin resistance, type 2 diabetes, heart disease, and declining liver health.

Benefits of Lower Branched-Chain Amino Acids (BCAAs)
Risks Linked to High BCAAs Benefits of Lower BCAAs
Insulin resistance Improved insulin sensitivity
Type 2 diabetes Lower diabetes risk
Heart disease Lower cardiovascular risk
Declining liver health Improved liver function

Conclusion: Coffee’s Divergent Hormonal Effects

The study confirms that coffee has hormonal effects that differ between men and women. For men, coffee appears supportive of testosterone levels and metabolic health. For women, it may be linked to hormonal changes that affect libido and mood.

On the positive side, coffee was linked to lower branched-chain amino acids in both sexes. This reduction may contribute to lowering the risks of insulin resistance, diabetes, and heart disease. Further studies are needed to understand the precise mechanisms behind these effects.

Frequently Asked Questions

Does coffee raise testosterone in men?Yes, the study showed significant increases in total testosterone and SHBG levels in men who regularly consume coffee.

How does coffee affect hormones in women?In women, coffee was linked to increased SHBG and decreased free androgens, which are responsible for libido, mood, and body, hair, and bone health.

What are branched-chain amino acids (BCAAs)?They are amino acids whose elevated levels are linked to risks of insulin resistance, diabetes, and heart disease. The study showed lower levels in coffee drinkers.

Are coffee’s hormonal effects dependent on lifestyle?No, the study showed that hormonal effects remained significant even after excluding lifestyle factors and body mass index.

How many participants were in the study?The study included over 2,200 participants aged 46, giving the results good statistical power.

Where was the study published?The study was published in the European Journal of Nutrition, a peer-reviewed scientific journal specializing in nutrition and health.

3 to 5 Cups of Coffee Daily Extend Life and Reduce Disease Risk

Dubai, 27 August 2025 (Qahwa World) – For centuries, coffee has been more than a drink. It has been a ritual, a social bond, a fuel for intellectual debate, and a daily companion for billions. Now, science is reaffirming that this centuries-old beverage is not only cultural but also profoundly tied to human health. A comprehensive review published this month in Nutrients concludes that moderate coffee consumption, typically three to five cups a day, is consistently linked to longer life and a reduced risk of many of the world’s leading causes of death.

The study, authored by Ryan Emadi and Dr. Farin Kamangar, examined decades of large-scale cohort research involving millions of participants across the United States, Europe, and Asia. Their findings show that people who regularly drink coffee enjoy between 10% and 15% lower overall mortality than non-drinkers. Importantly, both caffeinated and decaffeinated coffee were associated with these benefits, suggesting that the protective effects come not only from caffeine but also from the dozens of bioactive compounds present in coffee.

Evidence is particularly strong when it comes to major chronic diseases. For cardiovascular health, those who consumed three to five cups daily experienced about a 15% reduced risk of heart disease and stroke. Type 2 diabetes, a condition that affects hundreds of millions worldwide, also appears to be strongly influenced by coffee habits. A meta-analysis of more than one million participants found that coffee drinkers had nearly a 30% lower risk of developing type 2 diabetes, and this protection extended to both decaf and regular coffee. Among people already living with diabetes, coffee consumption was linked to fewer cardiovascular events and lower mortality rates.

The benefits extend to neurological health as well. Drinking coffee was associated with up to a 25% lower risk of cognitive disorders such as dementia and Alzheimer’s disease. The protective effect also applied to Parkinson’s disease, where coffee and caffeine intake not only lowered the risk of developing the disease but also slowed its progression among those already diagnosed. Respiratory diseases, another major global killer, also showed an inverse relationship with coffee consumption, while studies reported reduced risks of liver fibrosis, chronic kidney disease, and acute kidney injury among habitual drinkers.

Cancer, once the focus of skepticism about coffee, has now largely been cleared from suspicion. Earlier fears that coffee might contribute to cancer risk have been replaced by evidence suggesting the opposite. Coffee is now associated with reduced risk of several cancers, particularly of the liver, uterus, and endometrium. A pooled analysis of nineteen studies found that women who drank coffee had a 13% lower risk of endometrial cancer, and the relationship was dose-dependent—the more coffee, the lower the risk.

Beyond chronic disease, coffee also appears to play a role in everyday well-being and safety. Studies cited in the review showed that drivers consuming caffeinated coffee were significantly less likely to crash, and older adults had a reduced risk of falls. Researchers attribute this to coffee’s ability to improve alertness, attention, and mobility.

The mechanisms behind these benefits are diverse and interconnected. Coffee has been shown to improve glucose tolerance, enhance daily physical activity, increase fat oxidation during exercise, boost lung function, and reduce inflammation. One trial found that people who drank caffeinated coffee walked an average of 1,000 more steps per day than on days they abstained. Other studies demonstrated that coffee drinkers had lower levels of inflammatory markers, suggesting that coffee helps the body manage the underlying inflammation that fuels many chronic diseases.

Yet not all coffee is created equal. The review stressed that black coffee offers the strongest protection. Adding sugar, in particular, can cancel out or diminish benefits. Some studies have linked sugar-sweetened coffee to higher risks of depression and weight gain, while unsweetened coffee showed the opposite effect. Cream and milk appear less harmful, but excessive amounts of sugar and high-fat additives weaken coffee’s health profile.

There are also caveats. Pregnant women are advised to limit caffeine to below 200 milligrams per day, as higher intake may pose risks. Coffee can interfere with sleep if consumed too late in the day, cutting total sleep time by around 30 to 45 minutes. Excessive consumption may trigger anxiety, palpitations, or panic attacks in sensitive individuals. Despite these concerns, the authors emphasized that for the vast majority of adults, moderate consumption is not only safe but beneficial.

Dr. Farin Kamangar summarized the findings: “The results of several decades of high-quality research on millions of people show that coffee is overall beneficial to health. Moderate coffee consumption, typically three to five cups a day, is linked to increased longevity and reduced risks of many major diseases, including heart disease, stroke, type 2 diabetes, respiratory illnesses, and cognitive decline.”

This new consensus has already begun to reshape official guidelines. The U.S. Food and Drug Administration recently ruled that plain coffee with fewer than five calories per serving can be labeled as “healthy,” reflecting its favorable profile across multiple health outcomes.

In the end, coffee is not a cure-all, but the evidence is clear: consumed in moderation, it is far more friend than foe. For billions who reach for a cup each morning, the comfort of coffee now comes with scientific reassurance that it may also be extending their lives.